Effect of single dose versus continuous infusion of dexmedetomidine for reduction in incidence of emergence agitation in adults following nasal surgeries: A randomized double-blind study

Introduction: Emergence agitation is a serious post-anaesthetic event occurring in the early phase of recovery from general anesthesia. If untreated, this may result significant morbidity.Aim: To compare effect single dose versus continuous infusion dexmedetomidine for reduction incidence emergence adults following nasal surgeries.Methods: This study was conducted on 62 patients 20-60 years, randomly divided into two groups (31 each group), with ASA physical status I, II who were scheduled elective surgeries under anaesthesia. Group S received iv 1μg/kg 10 ml saline, over min before induction anaesthesia, while group C 0.5μg/kg 20 saline as anaesthesia up to time extubation. Incidence recorded primary outcome along severity agitation, sedation score, adverse effects and hemodynamic parameters secondary outcomes.Results: lower C, 8 (25.80% 6.45%) compared S, 15 (48.38% 19.35%), (p>0.05). Haemodynamic variables, mean score side complications comparable between groups.Conclusion: Dexmedetomidine more effective reducing dexmedetomidine.